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So, here’s the million-dollar question: How much of **TNBC** is actually linked to our genes? Here's the deal, guys: while most breast cancers are not directly caused by inherited genes, a significant portion of TNBC cases are linked to inherited gene mutations. We’re talking mainly about mutations in the BRCA1 and BRCA2 genes, which are known as breast cancer susceptibility genes. If you have a mutation in one of these genes, you have a much higher risk of developing breast cancer, including TNBC, as well as ovarian cancer. Roughly 5–10% of all breast cancers are thought to be hereditary, and a larger portion of TNBC cases are related to inherited gene mutations. Several studies suggest that around 10–20% of TNBC cases are due to inherited mutations in the BRCA1 or BRCA2 genes. This means that a considerable number of TNBC diagnoses have a strong genetic component. The exact percentage can vary based on the population studied and the specific criteria used, but it's clear that genetics play a bigger role in TNBC than in some other types of breast cancer.
